BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.
BMS-754807
CAS:1001350-96-4
Molecular Weight (MW):461.49
Formula:C23H24FN9O
Solubility :DMSO
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